Non-tuberculous Mycobacterial Lung Disease Presenting as a Solitary Pulmonary Nodule.
- Author:
Song Yee KIM
1
;
Kyung Jong LEE
;
Sang Hoon LEE
;
Sang Kook LEE
;
Byung Hoon PARK
;
Ji Ye JUNG
;
Ji Young SON
;
Yoe Wun YOON
;
Hyo Sup SHIM
;
Young Ae KANG
;
Moo Suk PARK
;
Young Sam KIM
;
Joon CHANG
;
Se Kyu KIM
;
Jin Wook MOON
Author Information
- Publication Type:Case Report
- Keywords: Mycobacterium Infections, Atypical; Solitary Pulmonary Nodule; Tuberculosis
- MeSH: Adult; Biopsy; Clarithromycin; Cough; Ethambutol; Follow-Up Studies; Humans; Inflammation; Isoniazid; Lung; Lung Diseases; Male; Mycobacterium avium Complex; Mycobacterium Infections, Nontuberculous; Necrosis; Pyrazinamide; Rifampin; Solitary Pulmonary Nodule; Sputum; Thorax; Tuberculosis; Tuberculosis, Pulmonary
- From:Tuberculosis and Respiratory Diseases 2010;69(1):43-47
- CountryRepublic of Korea
- Language:Korean
- Abstract: We report a case of Mycobacterium intracellulare pulmonary infection presenting as a solitary pulmonary nodule (SPN). A 35-year-old male was admitted due to a SPN in the right upper lobe which was detected on the chest radiography being examed due to recurrent cough for 1 year. The computed tomography (CT) revealed a spiculated nodule containing air-bronchogram, which was suspicious of malignancy. We performed transbronchial biopsy and the pathology showed granulomatous inflammation with caseous necrosis. Under the presumptive diagnosis of pulmonary tuberculosis, we started anti-tuberculous medication including isoniazid, rifampin, ethambutol, and pyrazinamide. In one month, however, the sputum culture was positive for Mycobacterium intracellulare. The follow-up chest CT showed slight aggravation of the previous lesions. Under the final diagnosis of Mycobacterium intracellulare pulmonary infection presenting as a solitary pulmonary nodule, we changed the regimen to rifampin, ethambutol, and clarithromycin. The follow-up chest CT after the completion of treatment, revealed resolution of the previous lesions.
