Differences in Clinical and Laboratory Findings between Group D and Non-Group D Non-Typhoidal Salmonella Gastroenteritis in Children.
10.5223/pghn.2015.18.2.85
- Author:
Heung Keun PARK
1
;
Kyuyol RHIE
;
Jung Sook YEOM
;
Ji Sook PARK
;
Eun Sil PARK
;
Ji Hyun SEO
;
Jae Young LIM
;
Chan Hoo PARK
;
Hyang Ok WOO
;
Hee Shang YOUN
;
Ki Ryeon KANG
;
Jung Je PARK
Author Information
1. Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, Korea. seozee@gnu.ac.kr
- Publication Type:Original Article
- Keywords:
Salmonella infection;
Salmonella enterica;
Gastroenteritis
- MeSH:
C-Reactive Protein;
Child*;
Fever;
Gastroenteritis*;
Gastrointestinal Hemorrhage;
Headache;
Humans;
Leukocyte Count;
Retrospective Studies;
Salmonella enterica;
Salmonella Infections;
Salmonella*
- From:Pediatric Gastroenterology, Hepatology & Nutrition
2015;18(2):85-93
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To investigate the differences in clinical features and laboratory findings between group D and non-group D non-typhoidal Salmonella (NTS) gastroenteritis in children. METHODS: A retrospective chart review of children diagnosed with NTS confirmed by culture study was performed. The clinical features and laboratory findings of group D and non-group D NTS were compared. RESULTS: From 2003 to 2012, 75 cases were diagnosed as NTS at our center. The number of group D and non-group D patients was 45 and 30, respectively. The mean age was higher in group D than in non-group D patients (5.1 years vs. 3.4 years, p=0.038). Headaches were more frequently observed (p=0.046) and hematochezia was less frequently observed (p=0.017) in group D than in non-group D NTS gastroenteritis patients. A positive Widal test result was observed in 53.3% of group D and 6.7% of non-group D NTS cases (O-titer, p=0.030; H-titer, p=0.039). There were no differences in white blood cell counts, level of C-reactive protein and rate of antimicrobial resistance between group D and non-group D cases. CONCLUSION: The more severe clinical features such as headache, fever, and higher Widal titers were found to be indicative of group D NTS gastroenteritis. Additionally, group D NTS gastroenteritis was more commonly found in older patients. Therefore, old age, fever, headache, and a positive Widal test are more indicative of group D NTS than non-group D NTS gastroenteritis. Pathophysiological mechanisms may differ across serologic groups.
