Radiation effect on the stages of amelogenesis in the rat incisor.
- Author:
Hyun Bae CHOI
1
;
Soon Chul CHOI
;
Tae Won PARK
;
Dong Soo YOU
Author Information
1. Department of Oral and Maxillofacial Radiology, College of Dentistry, Seoul National University, Korea.
- Publication Type:Original Article
- MeSH:
Ameloblasts;
Amelogenesis*;
Animals;
Cell Membrane;
Dentin;
Gamma Rays;
Incisor*;
Mitochondria;
Nuclear Envelope;
Radiation Effects*;
Rats*
- From:Journal of Korean Academy of Oral and Maxillofacial Radiology
1997;27(1):203-216
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purpose of this study was to investigate the radiation effect on the stages of amelogenesis. Twenty 11-day-old rats which were irradiated by 4GY of gamma radiation on the 19th prenatal day were used for the experimental group and twenty 11-day-old rats which were not irradiated were used for the control group. The length of each zone of amelogenesi s were measured on the sagittal section using a light microscopic enlargement at 400 X the normal view while the morphol ogic changes of ameloblasts of each zone were observed electron-microscopically. The obtined results were as followed: 1. The length of the region of facing pulp and facing dentin of the zone of presecretion were increased by 11.5%(P<0.05) and 17.7%(P<0.01), respectively. 2. The length of the zone of secretion was increased by 17.3%(P<0.01), but the zone of maturation was decreased by 15.3%(P<0.01). 3. The total length of the zone of amelogenesis was not changed significantly(P>0.05). 4. Electron-microscopically, enlargement of the cell membrane, rER, mitochondria, and nuclear membrane were observed. These changes were mostly severe in the zone of maturation.
