Multimodal Treatment of Skull Base Inflammatory Pseudotumor: Case Report.
10.14791/btrt.2015.3.2.122
- Author:
Sang Gun LEE
1
;
Il Young SHIN
;
Hyung Sik HWANG
;
Il CHOI
Author Information
1. Department of Neurosurgery, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong, Korea. kosaken@lycos.co.kr
- Publication Type:Case Report
- Keywords:
Granuloma;
Central nervous system;
Sphenoid sinus;
Cavernous sinus
- MeSH:
Amphotericin B;
Biopsy;
Brain;
Cavernous Sinus;
Central Nervous System;
Combined Modality Therapy*;
Dexamethasone;
Drug Therapy;
Follow-Up Studies;
Granuloma;
Granuloma, Plasma Cell*;
Humans;
Hydrocephalus;
Middle Aged;
Orbit;
Skull Base*;
Skull*;
Sphenoid Sinus;
Tuberculosis;
Ventriculoperitoneal Shunt
- From:Brain Tumor Research and Treatment
2015;3(2):122-126
- CountryRepublic of Korea
- Language:English
-
Abstract:
lnflammatory pseudotumor (IPT) is a rare, non-neoplastic inflammatory process. It is most commonly occurs in the orbit, but extension into brain parenchyma is uncommon. In a confirmed case of IPT, most cases show good improvement with steroid theraphy. A 50-year-old man with progressive left-eye visual disturbance and mass lesion was admitted in a hospital. A left orbital mass biopsy revealed what was highly suspected as an inflammatory pseudotumor. Steroid pulse therapy with dexamethasone, radiation therapy, and chemotherapy with amphotericin B were performed, but they were not effective in improving the condition of the patient. Revision open surgery was then performed. A follow-up brain enhancement computerized tomography showed an enlarged mass volume and hydrocephalus with periventricular enhancement. As an additional procedure, ventriculoperitoneal shunt and tuberculosis medication were administered. About 2 weeks later, clinical symptoms and radiologic findings improved. We present a case of intra-cranial IPT and discuss further treatment methods.
