Cerebellar encephalopathy from diminazene aceturate (beneril) toxicity in a dog.
- Author:
Donghyun HAN
1
;
Won Kyoung YOON
;
Changbaig HYUN
Author Information
1. Section of Small Animal Internal Medicine, Institute of Veterinary Science, College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University, Chuncheon 200-701, Korea. hyun5188@kangwon.ac.kr
- Publication Type:Case Report
- Keywords:
beneril;
cerebellar ataxia;
cerebellar encephalopathy;
diminazene aceturate;
dog
- MeSH:
Anemia;
Animals;
Ataxia;
Blood Transfusion;
Cerebellar Ataxia;
Cerebellum;
Depression;
Diminazene*;
Dogs*;
Humans;
Magnetic Resonance Imaging;
Male;
Paresis
- From:Korean Journal of Veterinary Research
2014;54(3):193-196
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 2-year old castrated male Alaskan malamute was referred with primary complaints of marked anemia, hemeglobinuria and depression. Laboratory tests revealed canine babesiois with severe anemia. The dog was treated by blood transfusion and beneril (diminazene aceturate, 3.5 mg/kg IM). Two days after Beneril injection, the dog suddenly showed ataxia progressing to paresis. MRI revealed irregularly diffused lesions in the cerebellum. The case was tentatively diagnosed as cerebellar encephalopathy caused by diminazene toxicity. The dog successfully recovered following steroid therapy.
