Evaluation of Urea Breath Test for the Detection of Helicobacter pylori Infection.
- Author:
Jongwook LEE
;
Nam Keum LEE
;
Soo Hwan PAI
;
Pum Soo KIM
;
Won CHOI
;
Don Hang LEE
;
Hyung GIL
;
Young Soo KIM
- Publication Type:Original Article
- Keywords:
Helicobacter pylori;
Urea breath test
- MeSH:
Biopsy;
Breath Tests*;
Gastritis;
Helicobacter pylori*;
Helicobacter*;
Humans;
Peptic Ulcer;
Sensitivity and Specificity;
Urea*;
Urease
- From:Korean Journal of Clinical Microbiology
2000;3(2):111-115
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Helicobacter pylori (H. pylori) is closely associated with gastritis, peptic ulcer and gastric carcinoma. We evaluated the reliability and usefulness of 73C-urea breath test (13C-UBT) for the detection of H. pylori infection and searched for the cut-off value of the test. METHOD : We investigated 45 patients, who underwent esophagoduodenoscopy with multiple biopsy specimens taken for culture, histology and rapid urease test, and 13C-UBT. Sensitivity and specificity of UBT were calculated against the combined biopsy-based test results. RESULT: Of 45 patients, 26 were found to be H. pylori-positive according to combined biopsy-based test-results. Sensitivity and specificity of the 13C-UBT were 100.0% and 89.5 %, respectively. CONCLUSION: The urea breath test provides a simple and reliable and noninvasive method of assessing HL pylori infection status.
