A Case of Leukocytoclastic Vasculitis after Influenza Vaccination.
- Author:
Hak Jun KIM
1
;
Sang Jun PARK
;
Jung Hyun KIM
;
In Gyun NA
;
Sun Young KIM
Author Information
1. Department of Internal Medicine, Ulsan Dong Kang Hospital, Ulsan, Korea. gogozip@hanmail.net
- Publication Type:Case Report
- Keywords:
Influenza vaccination;
Leukocytoclastic vasculitis
- MeSH:
Adult;
Biopsy;
Diagnosis;
Enzyme-Linked Immunosorbent Assay;
Female;
Fever;
Humans;
Immunoglobulin E;
Influenza, Human*;
Kidney;
Myalgia;
Nervous System;
Pleurisy;
Prognosis;
Recurrence;
Skin;
Vaccination*;
Vasculitis*
- From:The Journal of the Korean Rheumatism Association
2006;13(2):177-181
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We describe a 28 year-old woman who had fever, general myalgia, tender erythematous subcutaneous nodules on whole body skin, and acute pleuritis after influenza vaccination. Temporal association between vaccination and her symptoms and skin biopsy result are in agreement with our diagnosis as leukocytoclastic vasculitis. A review found that there were a few similar cases involving the skin, kidney, and rarely nervous system, mostly with good prognoses. Our patient was treated by a short course of corticosteroid and no recurrence has been observed for five months. Although there is a possibility of an infection, the temporal association, the false-positive HCV ELISA test, and the increased serum IgE were interesting findings, which might account for this leukocytoclastic vasculitis after influenza vaccination.