A Case of Allergic Contact Dermatitis Due to Topical Antifungal Cream.
- Author:
Joo Hyun SHIM
1
;
Han Gyu CHOI
;
Seong Jun SEO
;
Chang Kwun HONG
Author Information
1. Department of Dermatology, College of Medicine, Chung-Ang University Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Allergic contact dermatitis;
Propylene glycol;
Isoconazole nitrate
- MeSH:
Dermatitis, Allergic Contact*;
Female;
Humans;
Hypersensitivity;
Ketoconazole;
Leg;
Patch Tests;
Propylene Glycol;
Skin;
Young Adult
- From:Korean Journal of Dermatology
2000;38(8):1140-1143
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Propylene glycol, which is capable of producing both primary irritant and allergic skin reaction, is a common used vehicle for numerous topical preparations. The topical imidazole antimycotics are widely used but an infrequent cause of contact allergy. A 20-year-old female presented with erythematous scaly patch on the lower leg. An erythematous pruritic papulovesicular eruption developed around the lesion after applying Nizoral cream and was aggravated after applying Travogen cream. Patch test with Korean standard series and the ingredients of both cream revealed positive reaction to the propylene glycol contained in Nizoral cream and isoconazole nitrate in Travogen cream.
