Craniospinal Metastasis from a Metastasizing Mixed Tumor of Salivary Gland : Unusual Presentation.
10.3340/jkns.2007.41.3.186
- Author:
Hyun Hee YE
1
;
Chang Won CHO
;
Mi Young JEON
;
Dae Jo KIM
Author Information
1. Department of Neurosurgery, Maryknoll Medical Center, Busan, Korea. braincwc@hotmail.com
- Publication Type:Case Report
- Keywords:
Metastasizing mixed tumors;
Metastasis;
Primary tumor;
Cranial
- MeSH:
Mortality;
Neoplasm Metastasis*;
Recurrence;
Salivary Glands*;
Skull;
Spine
- From:Journal of Korean Neurosurgical Society
2007;41(3):186-189
- CountryRepublic of Korea
- Language:English
-
Abstract:
Metastasizing mixed tumors (MMT) of salivary glands are inexplicably metastasize maintaining benign histology. There is no pathologic and flow cytometric analysis criteria to predict the metastasis. MMT is known to metastasize by local implantation, vascular and lymphatic embolization after multiple surgery to local recurrences of primary tumor. However, multiple metastasis including cranium and spine occurred even without surgery to the primary tumor in this case. No pathological evidence of malignancy could be found in both primary and metastatic tumor. MMT is considered as an low grade malignancy based on clinical behavior rather than histologic evidence, such as low mortality rate, long delay of metastasis after primary lesion. Cranial metastasis is also extremely rare and only two cases have been reported. We report this unusual case with a literature review.
