Clinical Experiences of Pancreatic Tumors in Children.
- Author:
Ra Joo IM
1
;
Hae Sol KIM
;
Tae Seok KIM
;
Cheol Gu LEE
;
Jeong Meen SEO
;
Suk Koo LEE
Author Information
1. Division of Pediatric surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. sklee@smc.samsung.co.kr
- Publication Type:Original Article
- Keywords:
Pancreatic tumor;
Children;
Pancreatic resection
- MeSH:
Abdominal Pain;
Adenoma;
Adult;
Chemotherapy, Adjuvant;
Child*;
Cholangiopancreatography, Endoscopic Retrograde;
Cystadenocarcinoma, Mucinous;
Diagnosis;
Electroencephalography;
Female;
Follow-Up Studies;
Head;
Humans;
Ileus;
Insulinoma;
Jaundice;
Magnetic Resonance Imaging;
Male;
Pancreas;
Pancreatectomy;
Pancreaticoduodenectomy;
Pancreatitis;
Postoperative Complications;
Prognosis;
Pylorus;
Radiotherapy;
Rhabdomyosarcoma;
Survival Rate;
Wounds and Injuries
- From:Journal of the Korean Association of Pediatric Surgeons
2007;13(2):155-161
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pancreatic tumors in children are very rare but have a better prognosis compared with that in adult. Pediatric pancreatic tumors are more often benign and easier to resect. To evaluate the characteristics and prognosis, the records of 13 patients who underwent pancreatic resection, from June 1997 to May 2005, at Samsung Medical Center were reviewed. The mean follow up period was 48 months. The male to female ratio was 1: 1.6. Mean age was 10.3 years. Signs and symptoms included abdominal pain (7), abdominal palpable mass (5), jaundice (1), hypoglycemic (1), and non-specific GI symptoms (4). The commonly used diagnostic tools were CT and abdominal sonography. In addition, MRI, ERCP, EEG, and hormone test were also done when indicated. Surgical procedures included distal pancreatectomy (5), pylorus preserving pancreaticoduodenectomy (4), tumor excision (3), and subtotal pancreatectomy (1). Locations of lesions in pancreas were head (4), tail (5), and body and tail (4). Postoperative complications developed in 3 cases; postoperative ileus (1), wound problem (1), and pancreatitis (1). The pathologic diagnosis included solid-pseudopapillary tumor (6), congenital simple cyst (1), pancreatic duplication cyst (1), serous oligocystic adenoma (1), mucinous cystadenocarcinoma (1), rhabdomyosarcoma (1), insulinoma (1), and pancreatoblastoma (1). Three cases received adjuvant chemotherapy and radiotherapy. Overall survival rate was 81%. One patient with a mucinous cystadenocarcinoma died. In this study, pancreatic tumors in children were resectable in all patients and had good survival. Surgery of pancreatic tumors should be regarded as the gold standard of treatment and a good prognosis can be anticipated in most cases of benign and malignant tumors.
