A Case of Cholangiocarcinoma Suspected by Continuous Elevation of CA 19-9 after Surgery of Xanthogranulomatous Cholecystitis.
10.4166/kjg.2010.55.6.404
- Author:
Sang Youn HWANG
1
;
Joon Suk KIM
;
Ji Bong JEONG
;
Ji Won KIM
;
Byeong Gwan KIM
;
Kook Lae LEE
;
Young Joon AHN
;
Mee Soo CHANG
Author Information
1. Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Case Report ; English Abstract
- Keywords:
Cholecystitis, xanthogranulomatous;
CA 19-9;
Cholangiocarcinoma
- MeSH:
Bile Duct Neoplasms/*diagnosis/pathology/radiography;
*Bile Ducts, Intrahepatic;
CA-19-9 Antigen/*blood;
Cholangiocarcinoma/*diagnosis/pathology/radiography;
Cholecystitis/pathology/*surgery;
Granuloma/pathology/*surgery;
Humans;
Male;
Middle Aged;
Positron-Emission Tomography;
Tomography, X-Ray Computed;
Xanthomatosis/pathology/*surgery
- From:The Korean Journal of Gastroenterology
2010;55(6):404-409
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Xanthogranulomatous cholecystitis (XGC) is an unusual and destructive inflammatory process that is characterized by thickening of the gallbladder (GB) wall with a tendency to adhere to neighboring organs. XGC is often mistaken for GB carcinoma, and the frequency of the coexistence of these two lesions is approximately 10%. Therefore, in case of severe XGC, there is chance of either overlooking the carcinoma or other significant lesions. CA 19-9 is commonly measured in the serum of patients with hepatobiliary malignancies. Although CA 19-9 can be elevated in benign conditions such as cholestasis, pancreatitis, tuberculosis, thyroid disease etc., malignancy should be considered at first in setting of its significant and persistent elevation. We report a case of a 62-year-old man who showed continuously rising level of CA19-9 over 2000 U/mL after cholecystectomy for xanthogranulomatous cholecystitis and finally was diagnosed as cholangiocarcinoma by short-term follow up.
