Two Cases of Enterobacter hormaechei Infection Misidentified as Cedecea davisae Infection.
- Author:
Yong Kwan LIM
1
;
Oh Joo KWEON
;
Mi Kyung LEE
;
Kyoung Un PARK
Author Information
- Publication Type:Case Report
- Keywords: Enterobacteriaceae; Cedecea davisae; Enterobacter hormaechei; VITEK II; Sequence analysis
- MeSH: Bacteria; Cholecystitis, Acute; Enterobacter*; Enterobacteriaceae; Humans; Mass Spectrometry; Sequence Analysis; Venous Thrombosis
- From:Laboratory Medicine Online 2015;5(4):223-226
- CountryRepublic of Korea
- Language:Korean
- Abstract: Enterobacteriaceae is a family of gram-negative, rod-shaped bacteria that consists of various species. Among these, members of the genus Cedecea has been reported as relatively rare causative pathogens of human infections. Commercially available automated identification systems that use biochemical reactions are known to accurately identify Enterobacteriaceae species. However, the accurate identification of some organisms with diverse biochemical profiles by these automated identification systems may be problematic. In this study, we report two cases of isolate misidentification, from patients with acute cholecystitis and deep vein thrombosis, as Cedecea davisae with VITEK II system. Both the isolates were correctly identified as Enterobacter hormaechei using gyrB gene sequence analysis. We also performed 16S rRNA sequence analyses and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analyses; however, indeterminate results were obtained from both the assays. Therefore, the sequence analysis of alternative genes, like gyrB, might be useful for accurate identification of species that belong to the family of Enterobacteriaceae.
