Successful surgical correction of anal atresia in a transgenic cloned piglet.
- Author:
Gab Sang LEE
1
;
Hye Soo KIM
;
So Hyun LEE
;
Dae Yong KIM
;
Kang Moon SEO
;
Sang Hwan HYUN
;
Sung Keun KANG
;
Byeong Chun LEE
;
Woo Suk HWANG
Author Information
1. Department of Theriogenology and Biotechnology, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea. bclee@snu.ac.kr.
- Publication Type:Brief Communication ; Research Support, Non-U.S. Gov't
- Keywords:
anal atresia;
cloned pig;
miniature pig;
nuclear transfer;
transgenic pig
- MeSH:
Animals;
Animals, Genetically Modified/*surgery;
Anus, Imperforate/genetics/surgery/*veterinary;
*Cloning, Organism;
Female;
Genetic Predisposition to Disease;
Swine/*abnormalities/genetics/*surgery
- From:Journal of Veterinary Science
2005;6(3):243-245
- CountryRepublic of Korea
- Language:English
-
Abstract:
Inbred strains of pig become indispensable for a wide range of biological studies. In biomedical science, it is generally accepted that somatic cell nuclear transfer(SCNT)technology with inbreed strain of pig is essential for xenotransplantation. In this study, we observed the anal atresia in a cloned pig which was derived from fetal fibroblast of inbreed miniature pig. A presumptive anal site of the cloned pig was excised and the rectum was sutured to apposed skin for treatment. This cloned piglet seemed to be normal with healthy status after surgery. This report can be useful for the treatment of anal atresia of cloned piglets.
