Large Cell Calcifying Sertoli Cell Tumor of the Testis: A Case Study and Review of the Literature.
- Author:
Dae Hyun SONG
1
;
Seong Muk JEONG
;
Jong Tak PARK
;
Gak Won YUN
;
Byoung Kwon KIM
;
Jong Sil LEE
Author Information
1. Department of Pathology, The Armed Forces Capital Hospital, Seongnam, Korea.
- Publication Type:Case Report
- Keywords:
Testis;
Sertoli cell tumor;
Immunohistochemistry
- MeSH:
Basement Membrane;
Cytoplasm;
Eosinophils;
Humans;
Immunohistochemistry;
Inhibins;
Keratins;
MART-1 Antigen;
Orchiectomy;
S100 Proteins;
Sertoli Cell Tumor*;
Testis*;
Vimentin;
X-Ray Film;
Young Adult
- From:Korean Journal of Pathology
2014;48(1):50-53
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 24-year-old man was admitted due to an incidentally detected mass in his left testis, which showed radiopaque calcification on plain X-ray film. Left orchiectomy was performed, and the resected testis contained a well-demarcated, hard mass measuring 1.1 cm. Histological analysis revealed that the tumor was composed of neoplastic cells, fibrotic stroma, and laminated or irregularly shaped calcific bodies. The individual cells had abundant eosinophilic or clear cytoplasm with round nuclei, each of which contained one or two conspicuous nucleoli. They were arranged in cords, trabeculae, clusters, and diffuse sheets. There were several foci of intra-tubular growth patterns, with thickening of the basal lamina. Immunohistochemically, the neoplastic cells were positive for S-100 protein and vimentin, focally positive for inhibin alpha, and negative for cytokeratin, CD10, and Melan-A. In addition to reporting this rare case, we also review the relevant literature regarding large cell calcifying Sertoli cell tumors.
