Thoracic nodal staging in non-small cell lung cancer by FDG-PET.
10.4046/trd.2000.49.3.290
- Author:
Ji Hoon YOO
;
Sung Youn KWON
;
Chul Gyu YOO
;
Choon Taek LEE
;
Young Whan KIM
;
Sung Koo HAN
;
Young Soo SHIM
- Publication Type:Original Article
- Keywords:
PET;
Non-small cell lung cancer;
CT
- MeSH:
Carcinoma, Non-Small-Cell Lung*;
Humans;
Magnetic Resonance Imaging;
Male;
Mediastinum;
Medical Records;
Sensitivity and Specificity;
Thoracotomy;
Tomography, X-Ray Computed
- From:Tuberculosis and Respiratory Diseases
2000;49(3):290-297
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Current non-invasive methods for evaluating the mediastinum by computed tomographic(CT) scan have limited sensitivity and specificity. The recently introduced PET was reported to be a more sensitive and specific method for the mediastinal staging of NSCLC(sensitivity:76-100%, specificity:81-100%) than CT or MRI. We assessed the usefulness of PET in the mediastinal staging of NSCLC. METHODS: We reviewed the medical records of NSCLC patients that had undertaken staging work-up by both CT and PET before thoracotomy between January 1997 and December 1998. A total of 23 patients were enrolled in the study(14 males and 7 females) with a mean age of 61±9 years. By comparing the clinical(CT and PET) and pathologic stagings, we evaluated the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of PET in thoracic nodal staging. RESULTS: Sensitivity, specificity, positive predicted value and negative predicted value were 38%, 40%, 25% and 50% respectively for computed tomography, and 50%, 60%, 30% and 69% for PET. The accuracy of FDG-PET in our study was lower than that reported by previous other studies. CONCLUSION: Tne addition of FDG-PET to CT scanning has limited benefit for the thoracic nodal staging of NSCLC, but its value in our study was lower than that observed by others.
