Co-development of autoimmune hepatitis and Sjogren's syndrome triggered by the administration of herbal medicines.
10.3350/cmh.2013.19.3.305
- Author:
Hyo Jeong OH
1
;
Young Mi MOK
;
Moon Seong BAEK
;
Ji Kyeong LEE
;
Bong Soo SEO
;
Tae Hyeon KIM
;
Keum Ha CHOI
;
In Kyeom HWANG
;
Ji Eun RA
;
Yong Reol OH
;
Yong Sung KIM
;
Eun Young CHO
;
Haak Cheoul KIM
;
Young Woo SOHN
Author Information
1. Department of Internal Medicine, Wonkwang University Sanbon Hospital, Wonkwang University College of Medicine, Gunpo, Korea. friendsoh@hanmail.net
- Publication Type:Case Reports ; Research Support, Non-U.S. Gov't
- Keywords:
Autoimmune hepatitis;
Sjogren's syndrome;
Herbal medicine
- MeSH:
Alanine Transaminase/blood;
Aspartate Aminotransferases/blood;
Azathioprine/therapeutic use;
Bilirubin/blood;
Female;
Hepatitis, Autoimmune/complications/*diagnosis/drug therapy;
*Herbal Medicine;
Humans;
Liver/pathology;
Liver Function Tests;
Middle Aged;
Prednisolone/therapeutic use;
Sjogren's Syndrome/complications/*diagnosis/drug therapy
- From:Clinical and Molecular Hepatology
2013;19(3):305-308
- CountryRepublic of Korea
- Language:English
-
Abstract:
Autoimmune hepatitis (AIH) has been reported in association with Sjogren's syndrome (SS). Drug-induced AIH has been rarely reported. A rare case of the co-development of AIH and SS in a 53-year-old woman after the consumption of herbal medicines is described. After admission, the patient complained of dryness in her mouth, and she was subsequently diagnosed with SS, which had not been detected previously. The patient's bilirubin and aminotransferase levels initially decreased following conservative management; however, they later began to progressively increase. A diagnosis of AIH was made based on the scoring system proposed by the International Autoimmune Hepatitis Group. The patient was administered a combination of prednisolone and azathioprine, and the results of follow-up liver-function tests were found to be within the normal range. This is an unusual case of AIH and SS triggered simultaneously by the administration of herbal medicines.
