Factors Influencing the Effect of the Intravitreal Bevacizumab Injection in Patients with Central Serous Chorioretinopathy.
10.3341/jkos.2014.55.3.391
- Author:
Eui Yong KWEON
1
Author Information
1. Department of Ophthalmology, Chonbuk National University Medical School, Jeonju, Korea. key@jbnu.ac.kr
- Publication Type:Original Article
- Keywords:
Bevacizumab;
Central serous chorioretinopathy
- MeSH:
Central Serous Chorioretinopathy*;
Fluorescein Angiography;
Follow-Up Studies;
Humans;
Macular Edema;
Medical Records;
Retrospective Studies;
Tomography, Optical Coherence;
Bevacizumab
- From:Journal of the Korean Ophthalmological Society
2014;55(3):391-395
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the factors influencing the effect of the intravitreal bevacizumab injection in patients with central serous chorioretinopathy. METHODS: We performed a retrospective review of the medical records of 54 patients (56 eyes) who had been symptomatic for more than 3 months with central serous chorioretinopathy (CSC), who had undergone intravitreal bevacizumab injection and been on regular follow-up for at least 6 months. RESULTS: Responders were 34 eyes (60.7%) and non-responders were 22 eyes (39.3%). The leaking points of the non-responder group were multiple and located more centrally than that of the responder group on fluorescein angiography (FA) (p = 0.01, p = 0.044). In addition, non-responder group showed cystoid macular edema on optical coherence tomography (OCT) as compared with responder group (p = 0.042). CONCLUSIONS: CSC with multiple, centrally located leaks on FA or cystoid macular edema on OCT was ineffective or recurrent with intravitreal bevacizumab injection.
