Failure Of Odontogenesis After Chemo-Radiation Therapy For Rhabdomyosarcoma.
- Author:
Sun Young CHOI
1
;
Sung Woo HONG
;
Kwang Joon KOH
Author Information
1. Department of Oral & Maxillofacial Radiology, College of Dentistry, Chonbuk National University, Korea.
- Publication Type:Original Article
- MeSH:
Child;
Cyclophosphamide;
Dactinomycin;
Dental Caries;
Dental Enamel;
Dental Enamel Hypoplasia;
Diagnosis, Oral;
Dislocations;
Drug Therapy;
Female;
Humans;
Molar;
Odontogenesis*;
Rhabdomyosarcoma*;
Tooth;
Tooth, Impacted;
Vincristine
- From:Journal of Korean Academy of Oral and Maxillofacial Radiology
1998;28(1):285-297
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This report details a case of 8-year-old girl showing failure of odontogenesis after chemo-radiation therapy for rhabdomysarcoma at the age of 4. The observed results were as follows ; 1. Past history revealed that she had received for a total radiation dose od 4430cGy, 29 fractions in 6 weeks and chemotherapy with vincristine, actinomycin D and cytoxan, followed as maintenance phase for 2 years. 2. The patient was symptom-free and appointed for the treatment of multiple dental caries. 3. Oral examination showed hypoplastic enamel on whole erupted permanent teeth and showed retarded eruption. 4. Conventional radiograms showed failure of root development including abrupt cessation of root formation and root agenesis, and microdobtia, missing teeth, irregular enamel, dislocation of the impacted teeth. Additional finding showed good healing bone pattern on the left mandibular ramus and angle area. 5. Cehalometric analysis revealed failure of bite raising due to incomplete eruption of all the first molars and made it possible to suspect entrapped mandibular growth and then Class II tendency growth. 6. There was correlation between the time of chemo-radiation therapy and the damage of the teeth.
