Study on the trial preparation of the lidocaine containing soluble tablet in the bowels for treatment of arrhythmia
- Author:
Tuan Trong Le
- Publication Type:Journal Article
- Keywords:
lidocaine
- MeSH:
Lidocaine;
Arrhythmia;
tablets;
therapeutics
- From:Journal of Vietnamese Medicine
2001;263(9):155-161
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Since 1975, lidocaine has been made up in Friendship hospital with the name rythmocardyl as a dissoluble tablet in the bowels. The magistral formula and processing procedures have been studied and tested to reach the VNP II - 1994 and BP-1993 standards. The lethal dosage (LD50), the anti - ventricular fibrillation and anti-arrhythmic effects, the blood concentration of lidocaine taken orally at different times as well as the dissolution of rythmocardyl in the human body have been tested experimentally. The research have proven that lidocaine, taken orally has few side effects and is safe and effective to treat the cardiac arrhythmia, notably the ventricular extrasystoles
