An Experimental Study on Late Change of the Irradiated Lung.
- Author:
Hong Sik BYUN
1
;
Charn Il PARK
;
Man Chung HAN
Author Information
1. Department of Radiology, College of Medicine, Seoul National University, Korea.
- Publication Type:Original Article
- MeSH:
Animals;
Exudates and Transudates;
Fibrosis;
Lung*;
Pleural Effusion;
Pulmonary Atelectasis;
Rats
- From:Journal of the Korean Society for Therapeutic Radiology
1983;1(1):5-10
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To evaluate late change of irradiated lung, a total of 60 rats was irradiated on right lungfield with a single dose of 2000 rads using Co-0 teletherapy unit. Follow-p roentgenographic and histopathologic study was performed three, six and twelve months after irradiation in each group of 20 rats. The results were as follows: 1.Chest roentgenographic findings in the order of frequency were pneumonic consolidation, atelectasis, and pleural effusion in 3-onth follow-p group; atelectasis, fibrostreaky infiltration, and pneumonic consolidation in 6-onth follow-p; and normal, and normal, and atelectasis in 12-onths follow-p group. 2. Main histopathological findings were alveolar and interstitial exudates, and diffuse infiltration of inflammatory cells in 3-onth follow-p group; thickening of interstitium and vascular wall in 6-onth follow-p group; and interstitial fibrosis in 12-onth follow-p group.
