Radiation Therapy of Midline Pineal Tumors and Suprasellar Germinoma.
- Author:
Chang Ok SUH
1
;
Gwi Eon KIM
;
Jung Ho SUH
;
Chang Yun PARK
;
Sung Sil CHU
Author Information
1. Department of radiology, Yonsei University Medical College, Korea.
- Publication Type:Original Article
- MeSH:
Biopsy;
Brain;
Germinoma*;
Humans;
Pinealoma*;
Radiotherapy;
Spinal Cord;
Tomography, X-Ray Computed
- From:Journal of the Korean Society for Therapeutic Radiology
1983;1(1):69-78
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
20 cases of midline pineal tumors and 3 suprasellar germinomas received radiation therapy at Yonsei University Medical College, Severance hospital from 1971 to 1982 were reviewed. 12 cases were pathologically proved; 10 germinomas, 1 pineoblastoma, and 1 pineocytoma. 11 cases received radiotherapy without biopsy confirmation. Although treatment fields varied from small field to whole brain irradiation, but not to the spinal cord, most patients received 4000-000 rads irradiation to the primary tumor site. 17 patients are alive without evidence of disease and 5 year actuarial NED survival is 73.2%. 9 of 10 biopsy proved germinomas and all 6 presumed germinomas are alive and well. Optimum radiation dose, adequate irradiation field, tumor response to radiation observed in serial CT scan and role of radiation therapy in the management of pineal tumors are also discussed.
