Aqueductal Atresia with Forking Anomaly: Report of 3 cases.
- Author:
Na Hye MYONG
;
Mi Kyung KIM
;
Je G CHI
- Publication Type:Case Report
- Keywords:
Aquductal atresia with forking anomaly;
Congenital hydrocephalus;
Associated anomalies
- MeSH:
Female;
Male;
Humans
- From:Korean Journal of Pathology
1994;28(5):514-521
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Aqueductal forking was first described by Russell (l949) as a cause of aqueductal obstruction and a form of congenital malformation with simple stenosis, it is a relatively common cause of congenital hydrocephalus not associated with spina bifida or meningomyelocele. Pathologically it is characterized by two distinct channels separated by non-gliotic brain tissue. We describe variable clinicopathologic findings of 3 autopsy cases showing hydrocephaly due to aqueductal atresia with forking case 1 was a 35-week-old female showing Potter's syndrome, dextrocardia, and skeletal anomaly. case 2 was a 29-week-old male abortus with micrognathia, simian crease, club feet, and minor defects of visceral organs. Case 3 was a 32-week-old female abortus with associated anomalies such as a low-set ear, ectopic thymus and thyroid, and Meckel's diverticulum. On serial sections of brain stems of all 3 cases, were seen variably shaped and atretic lumina of aqueducts with distinct two channe1s and intervening brain tissues of normal cellularity.
