Nonsecretory Multiple Myeloma with Multiple Spine Fracture.
- Author:
Yong Seok HUH
1
;
Kwan Ho PARK
;
Moon Pyo CHI
;
Jae O KIM
;
Jung Chul KIM
Author Information
1. Department of Neurosurgery, Korea Veterans Hospital, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Multiple myeloma;
Nonsecretory;
Protein electrophoresis;
Protein immunoelectrophoresis;
Pathologic fracture
- MeSH:
Biopsy;
Biopsy, Needle;
Bone Marrow;
Diagnosis;
Electrophoresis;
Fractures, Compression;
Fractures, Spontaneous;
Humans;
Immunoelectrophoresis;
Incidence;
Low Back Pain;
Magnetic Resonance Imaging;
Multiple Myeloma*;
Neck Pain;
Plasma;
Plasma Cells;
Spine*
- From:Journal of Korean Neurosurgical Society
2001;30(12):1435-1438
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A case of nonsecretory multiple myeloma in a 66 year-old-woman is reported. At first, she complained severe neck pain and radiologic finding showed C2 pathologic fracture. She complained severe low back pain 4 month later and L1 compression fracture was found. The lumbar MRI showed a 1.4cm-sized round enhancing lesion in the body of T12. Bone marrow aspiration biopsy at L1 spine showed a few polymorphous and small nests of mononuclear cell. L1 lamina bone biopsy showed many abnormal plasma cells. Pathologic diagnosis was multiple myeloma. However, plasma electrophoresis and protein immunoelectrophoresis of serum and urine of patient were normal. So, it is a nonecretory multiple myeloma case and the incidence of nonsecretory multiple myeloma is known to about 1% of all multiple myeloma.
