Serum Prealbumin Affected More by Serum CRP Than by Residual Burned Surface Area.
- Author:
Kyung Tak YOO
1
;
Go Woon WOO
;
Tae Young JANG
;
Jae Seok SONG
Author Information
1. Department of General Surgery, Hanil General Hospital, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Electric burns;
Prealbumin;
Transthyretin;
Nutrition
- MeSH:
Biomarkers;
Burns*;
Burns, Electric;
C-Reactive Protein;
Hospitals, General;
Humans;
Lymphocyte Count;
Male;
Nutritional Status;
Nutritional Support;
Prealbumin*
- From:Journal of Korean Burn Society
2016;19(2):57-61
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Prealbumin is known as a biochemical marker for assessing nutritional status, and it is influenced by a systemic inflammatory condition. This study aims to find any correlation between patients' low serum prealbumin in electrical burn and unhealed burn surface area and insufficient nutritional support. METHODS: Data were collected by a review of the medical charts of patients admitted to Hanil General Hospital for electrical burn. Laboratory results such as prealbumin, albumin, total lymphocyte count (TLC), and C-reactive protein (CRP) were collected and tested every week. Residual burn surface area (residual BSA) during a specific period was calculated from the surgery record. Statistical analysis was conducted using Pearson's correlation and multiple regression analysis. RESULTS: A total of 30 subjects were selected, all male. Average total burn surface area was 20.9±14.9%, and patients were operated on about three times after admission. There was statistical significance among all variables in Pearson's correlation test, but in multiple regression analysis, albumin and CRP were significant compared with prealbumin. CONCLUSION: The results could indicate that burn causes a systemic inflammatory reaction, which could affect the serum prealbumin level. Further study concerning the biological plausibility of each variable is needed.
