Risk Factors Associated with Rhabdomyolysis in Acute Carbon Monoxide Poisoning.
- Author:
Gio HAN
1
;
Yeon Sik JANG
;
Jae Ho JANG
;
Yong Su LIM
;
Hyuk Jun YANG
Author Information
1. Department of Emergency Medicine, Gachon University Gil Hospital, Incheon, Korea. yanghj@gilhospital.com
- Publication Type:Original Article
- Keywords:
Carbon monoxide poisoning;
Rhabdomyolysis;
Duration of CO exposure
- MeSH:
Blood Pressure;
Body Temperature;
Carbon Monoxide Poisoning*;
Carbon Monoxide*;
Carbon*;
Carboxyhemoglobin;
Coma;
Emergency Service, Hospital;
Humans;
Hydrogen-Ion Concentration;
Kidney;
Leukocyte Count;
Logistic Models;
Poisoning;
Reference Values;
Retrospective Studies;
Rhabdomyolysis*;
Risk Factors*;
Troponin I
- From:Journal of Korean Burn Society
2016;19(2):67-72
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aim of this study was to determine the risk factors for rhabdomyolysis in patients with carbon monoxide (CO) poisoning. METHODS: This was a retrospective study on patients with CO poisoning who visited the emergency department from January 1, 2014 to December 31, 2015. We compared clinical variables between patients with and without rhabdomyolysis. RESULTS: Among 120 patients who were included to this study, 108 patients exhibited normal value of CPK (creatine phosphokinase), and 12 patients were diagnosed as rhabdomyolysis. Sources of CO, duration of CO exposure, initial GCS (Grasgow coma scale), initial systolic and diastolic blood pressure, initial body temperature and AKI (Acute kidney injury) were showed significant difference between patients who developed rhabdomyolysis and patients who did not. In addition, initial white blood cell counts, troponin I level and carboxyhemoglobin (COHb) level were more higher in rhabdomyolysis group. pH and initial bicarbonate level were more lower. Duration of CO exposure (Odds ratio, 1.011; 95% confidence interval, 1.002∼1.020, P=0.021)was found to be only risk factor for rhabdomyolysis by logistic regression analysis. CONCLUSION: Duration of CO exposure is potential risk factor of rhabdomyolysis development in CO poisoning.
