Effects of Dimethylpiperazinium on the Renal Function of Rabbits.
- Author:
Hi Kyung KIM
1
;
Sae Kook CHANG
Author Information
1. Department of Urology, Taegu Armed Forced General Hospital Taegu, Korea.
- Publication Type:Original Article
- Keywords:
renal function;
dimethylpiperazinium;
diuresis
- MeSH:
Dimethylphenylpiperazinium Iodide;
Diuresis;
Electrolytes;
Glomerular Filtration Rate;
Rabbits*;
Renal Circulation
- From:Korean Journal of Urology
1982;23(1):1-5
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In this study, effects of the intraventricular and intravenous dimethylphenylpiperazinium (DMPP) on the renal function of rabbits were investigated. Intraventricular DMPP (100 microgram) elicited diuresis following antidiuresis concomitant with the changes in renal blood flow, glomerular filtration rate and urinary excretory amount of electrolytes (Na and K). The changes in urine flow correlated with the changes in renal blood flow, glomerular filtration rate and excretory rates of electrolytes in urine. Intravenous DMPP (50 microgram/kg) did not affect the renal function.
