The Diagnostic Accuracy of the 64-slice Multi-detector CT Coronary Angiography for the Assessment of Coronary Artery Stenosis in Symptomatic Patients.
10.3348/jkrs.2008.59.4.225
- Author:
Sung Min KO
1
;
Jeong Geun YI
;
Chang Wook NAM
;
Dong Hoon KIM
Author Information
1. Department of Radiology, Konkuk University Hospital and Konkuk University School of Medicine, Korea. ksm9723@yahoo.co.kr
- Publication Type:Original Article
- Keywords:
Computed tomography (CT);
Coronary angiography;
Coronary vessels, CT;
Coronary vessels, stenosis or obstruction
- MeSH:
Angiography;
Chest Pain;
Constriction, Pathologic;
Coronary Angiography;
Coronary Artery Disease;
Coronary Stenosis;
Coronary Vessels;
Humans;
Sensitivity and Specificity
- From:Journal of the Korean Radiological Society
2008;59(4):225-234
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: We evaluated the diagnostic accuracy of a 64-slice multi-detector CT (MDCT) coronary angiography against a conventional coronary angiography (CCA) for the detection of significant stenosis (> or =50% lumen diameter narrowing). MATERIALS AND METHODS: Sixty-four patients underwent a MDCT and a subsequent CCA to evaluate the presence of atypical chest pain or suspected coronary artery disease (CAD). A MDCT angiography was performed using a 64-slice MDCT-scanner (Sensation 64, slice collimation 32x0.6 mm). The coronary artery segments were classified according to a 15-segment model. The sensitivity, specificity, and diagnostic accuracy of the 64-slice MDCT for the detection or exclusion of significant CAD were calculated on a per-segment and per-patient basis. RESULTS: Fifty-nine of the 64 (92%) coronary CT angiograms were of diagnostic image quality with 93.5% (809 of 865) of the coronary segments assessable by CT angiography. One-hundred two (12.6%) segments showed significant stenosis by CCA. Stenosis of 50% or greater was detected by sensitivity, specificity, accuracy, positive predictive valve, and negative predictive value on a per segment basis (89%, 99%, 97%, 90%, and 98%, respectively) and a per-patient basis (96%, 69%, 90%, 92%, and 82%, respectively). CONCLUSION: The 64-slice MDCT coronary angiography demonstrated a high diagnostic accuracy for both the per-segment and per-patient analyses for this symptomatic patient group.
