A Case of Central Diabetes Insipidus in a Patient with Systemic Lupus Erythematosus.
- Author:
Ji Hyun KIM
1
;
Young Jin NAM
;
Mi Ran KWON
;
Chan Hee LEE
;
Seong Hoon HAN
;
Won Do PARK
;
Byung Doo RHEE
;
Yun Woo LEE
Author Information
1. Department of Internal Medicine, College of Medicine, Inje University, Sanggye Paik Hospital, Seoul, Korea. shhan@sanggyepaik.or.kr
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Central diabetes insipidus
- MeSH:
Autoantibodies;
Autoimmune Diseases;
Brain Neoplasms;
Diabetes Insipidus, Neurogenic*;
Histiocytosis;
Humans;
Leukemia;
Lupus Erythematosus, Systemic*;
Lupus Vasculitis, Central Nervous System;
Pituitary Gland;
Vasculitis;
Vasopressins
- From:The Journal of the Korean Rheumatism Association
2002;9(3):220-224
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Central diabetes insipidus is caused by the insufficient secretion of vasopressin and has been reported in great variety of disorder of brain tumor, systemic infiltrative disease such as histiocytosis, amyoidosis and vasculitis, leukemia, and other autoimmune diseases. But there has been reported only 3 cases of systemic lupus erythematosus (SLE) associated with central diabetes insipidus. The exact pathophysiologic process of pituitary gland involvement in SLE has been unknown, although there are some evidence that vascular impairment and autoantibodies to pituitary gland may be contributory factors. Here, we report a case of central diabetes insipidus complicated by neuropsychiatric systemic lupus erythematosus.