Variety of the Wave Change in Compound Muscle Action Potential in an Animal Model.
- Author:
Zenya ITO
1
;
Shiro IMAGAMA
;
Kei ANDO
;
Akio MURAMOTO
;
Kazuyoshi KOBAYASHI
;
Tetsuro HIDA
;
Kenyu ITO
;
Yoshimoto ISHIKAWA
;
Mikito TSUSHIMA
;
Akiyuki MATSUMOTO
;
Satoshi TANAKA
;
Masayoshi MOROZUMI
;
Yukihiro MATSUYAMA
;
Naoki ISHIGURO
Author Information
- Publication Type:Original Article
- Keywords: Compound muscle action potential; Morphology change; Amplitude
- MeSH: Action Potentials*; Animals*; Contusions; Gravitation; Laminectomy; Models, Animal*; Spinal Cord
- From:Asian Spine Journal 2015;9(6):952-957
- CountryRepublic of Korea
- Language:English
- Abstract: STUDY DESIGN: Animal study. PURPOSE: To review the present warning point criteria of the compound muscle action potential (CMAP) and investigate new criteria for spinal surgery safety using an animal model. OVERVIEW OF LITERATURE: Little is known about correlation palesis and amplitude of spinal cord monitoring. METHODS: After laminectomy of the tenth thoracic spinal lamina, 2-140 g force was delivered to the spinal cord with a tension gage to create a bilateral contusion injury. The study morphology change of the CMAP wave and locomotor scale were evaluated for one month. RESULTS: Four different types of wave morphology changes were observed: no change, amplitude decrease only, morphology change only, and amplitude and morphology change. Amplitude and morphology changed simultaneously and significantly as the injury force increased (p<0.05) Locomotor scale in the amplitude and morphology group worsened more than the other groups. CONCLUSIONS: Amplitude and morphology change of the CMAP wave exists and could be the key of the alarm point in CMAP.
