A Case of Cryoglobulinemia on Unusual Sites.
- Author:
Young Hun KIM
1
;
Chan Woo LEE
;
Ki Hoon SONG
;
Ki Ho KIM
Author Information
1. Department of dermatology, College of medicine, Dong-A university, Busan, Korea. mucca@hanmail.net
- Publication Type:Case Report
- Keywords:
Cryoglobulinemia;
Multiple myeloma
- MeSH:
Aged;
Cryoglobulinemia*;
Elbow;
Female;
Gangrene;
Humans;
Immunoglobulins;
Knee;
Multiple Myeloma;
Purpura;
Rewarming;
Skin;
Ulcer
- From:Korean Journal of Dermatology
2002;40(10):1286-1288
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cryoglobulinemia refers to the presence in the serum of one or more immunoglobulins that precipitate at temperatures below 37degrees C and that redissolve on rewarming. Type I cryoglobulin contains an isolated monoclonal immunoglobulin. The symptoms of type I cryoglobulinemia included purpura, Raynaud's phenomenon, distal ulcerations and gangrenous change caused by vascular occlusion resulting from protein precipitation. We report a case of type I cryoglobulinemia in a 72-year-old woman who had purpuras and gangrenes on her right elbow and left knee without distal skin lesions.