Gastric Schwannoma.
10.3349/ymj.2008.49.6.1052
- Author:
Ho Young YOON
1
;
Choong Bai KIM
;
Yoon Hee LEE
;
Ho Guen KIM
Author Information
1. Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. cbkimmd@yuhs.ac
- Publication Type:Case Report ; Comparative Study
- Keywords:
Schwannoma;
stomach;
submucosal tumor;
S-100 protein
- MeSH:
Diagnosis, Differential;
Female;
Gastrointestinal Stromal Tumors/diagnosis;
Humans;
Immunohistochemistry;
Middle Aged;
Neurilemmoma/*diagnosis/metabolism;
S100 Proteins/metabolism;
Stomach Neoplasms/*diagnosis/metabolism
- From:Yonsei Medical Journal
2008;49(6):1052-1054
- CountryRepublic of Korea
- Language:English
-
Abstract:
Schwannomas, also known as neurinomas or neurilemmomas, are generally benign, slow-growing neoplasms originating in any nerve that has a Schwann cell sheath. These neoplasms are rare among the spindle cell mesenchymal tumors of the gastrointestinal tract, but develop most commonly in the stomach representing 0.2% of all gastric tumors. We present the case of a 57-year-old female patient with a large schwannoma in the stomach that was palpable in the abdomen. She underwent subtotal gastrectomy under suspicion of gastrointestinal stromal tumor (GIST), but post-operative histopathological and immunohistochemical findings showed a fascicular arrangement of spindle cell with pallisading nuclei, and positive for S-100 protein with negative smooth muscle actin (SMA). These results confirmed schwannoma as the diagnosis.
