Amphetamine-Like Weight Reduction Drug Induced Acute Cardiomyopathy with Left Ventricular Thrombosis.
10.12771/emj.2014.37.S.S37
- Author:
Jeong Min KIM
1
;
Sung Kee RYU
;
Jae Woong CHOI
;
Dong Geum SHIN
;
Yung Hee LEE
;
Hye Ran KANG
;
Won Young CHAE
;
Ji Sang PARK
Author Information
1. Department of Internal Medicine, Eulji University College of Medicine, Seoul, Korea. ysk1140@eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Amphetamine;
Cardiomyopathies;
Thrombosis
- MeSH:
Adult;
Amphetamine;
Angiotensins;
Cardiomyopathies*;
Diuretics;
Dyspnea;
Echocardiography;
Edema;
Female;
Heart Failure;
Heart Ventricles;
Heparin, Low-Molecular-Weight;
Humans;
Risk Factors;
Smoke;
Smoking;
Stroke Volume;
Thorax;
Thrombosis*;
Weight Loss*
- From:The Ewha Medical Journal
2014;37(Suppl):S37-S40
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 37-year-old female patient admitted due to dyspnea on exertion and peripheral edema. For one and a half years, the patient had been taking various drugs and supplements to reduce weight, including amphetamine-like drugs. The patient had no major cardiovascular risk factors except three pack-years of smoking. A chest computed tomography showed a 1.7 cm diameter, capsulated space-occupying lesion in the left ventricle (LV) and 2-dimensional echocardiography showed LV systolic dysfunction (Left ventricular ejection fraction [LVEF], 30%) with a mobile cystic mass (1.1x1.8 cm) that was attached to the LV apex, which was increased in size and number the next day, even with low dose low-molecular-weight heparin. With an increased dose of anticoagulation medication and heart failure management with diuretics and angiotensin receptor II blocker, LV dysfunction was recovered and the LV thrombus disappeared.
