A Case of Cholangiocarcinoma with Brain and Leptomeningeal Carcinomatosis.
- Author:
Dae Hyun BACK
1
;
Ki Young YANG
;
Ye Rim LEE
;
Su Yeon CHO
;
Kyung Ah LIM
;
Jun Su BYUN
;
Sun Hoo PARK
Author Information
1. Department of Internal Medicine, Korean Cancer Center Hospital, Seoul, Korea. gooddryang@naver.com
- Publication Type:Case Report
- Keywords:
Cholangiocarcinoma;
Cystic mass;
Brain metastasis;
Leptomeningeal carcinomatosis
- MeSH:
Biliary Tract;
Brain;
Cerebrum;
Cholangiocarcinoma;
Epithelium;
Follow-Up Studies;
Headache;
Humans;
Liver;
Liver Neoplasms;
Lung;
Lymph Nodes;
Meningeal Carcinomatosis;
Neoplasm Metastasis;
Occipital Lobe;
Prognosis
- From:Korean Journal of Medicine
2012;83(6):771-774
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cholangiocarcinoma is a malignant disease originating from the epithelium of the biliary tract, and its prognosis is dismal due to distant metastasis in its early stages. The most common metastatic sites are the intra-abdominal organs, lymph nodes, and lungs. A patient was diagnosed with intrahepatic cholangiocarcinoma and underwent surgical resection. During the follow-up period, metastases were detected at the remnant liver and both lung fields. Eleven months after resection, the patient complained of severe headache. An approximately 5-cm cystic mass was found at the left occipital lobe of the cerebrum, and metastatic malignant cells were present on cerebrospinal fluid cytology. The patient underwent whole-brain radiotherapy. We herein report a rare case of cholangiocarcinoma with cystic brain metastasis together with a review of the relevant literature.