A Case of a Calcitonin-Secreting Pancreatic Endocrine Tumor in a Pateint with Multiple Endocrine Neoplasia Type 1.
- Author:
Jun Hyeok CHOI
1
;
Hong Ik KIM
;
Sun Mi KANG
;
Seong Gyu KIM
;
Hoon Kyu OH
;
Sung Hwa BAE
;
Hun Mo RYOO
Author Information
1. Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea. rhmrhm@cu.ac.kr
- Publication Type:Case Report
- Keywords:
Calcitonin;
Pancreatic endocrine tumor;
MEN1
- MeSH:
Adenoma;
Adenomyosis;
Brain;
Breast;
Breast Neoplasms;
Calcitonin;
Carcinoid Tumor;
Carcinoma, Ductal;
Carcinoma, Papillary;
Female;
Humans;
Hypercalcemia;
Korea;
Magnetic Resonance Imaging;
Middle Aged;
Multiple Endocrine Neoplasia;
Multiple Endocrine Neoplasia Type 1;
Myoma;
Pancreas, Exocrine;
Parathyroid Glands;
Pituitary Gland, Anterior;
Thyroid Gland
- From:Korean Journal of Medicine
2012;83(6):817-822
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant hereditary disorder characterized by the combined occurrence of tumors of the parathyroid gland, exocrine pancreas, and anterior pituitary gland. Calcitonin-secreting pancreatic endocrine tumors are rare, and calcitonin-secreting pancreatic endocrine tumors with MEN1 have not been reported in Korea. A 46-year-old woman was admitted for a right breast cancer operation. Abnormal blood chemistry findings were hypercalcemia and elevated calcitonin. The patient was diagnosed with a calcitonin-secreting pancreatic endocrine tumor, left thyroid papillary carcinoma, right breast invasive ductal carcinoma, a thymic carcinoid tumor, left adrenal adenoma, uterine myoma, and adenomyosis by computed tomography scan, and with pituitary macroadenoma by brain magnetic resonance imaging. We present this case with a review of the literature, because it is the first reported calcitonin-secreting pancreatic endocrine tumor with MEN 1 in Korea.
