Platelet Dysfunction in a Patient with Multiple Myeloma: A Case Report with a Literature Review.
- Author:
Soo Young NA
1
;
Jin Wook PARK
;
Jun Seok CHOI
;
Dae Ho LEE
;
Hyun Sook CHI
;
Jung Shin LEE
;
Cheolwon SUH
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine, Seoul, Korea. csuh@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Multiple myeloma;
Paraproteinemias;
Hemostatic disorders;
Platelet function tests;
Plasmapheresis
- MeSH:
Blood Platelets;
Hemorrhage;
Hemostatic Disorders;
Humans;
Multiple Myeloma;
Paraproteinemias;
Paraproteins;
Plasma Cells;
Plasma Exchange;
Plasmapheresis;
Platelet Function Tests
- From:Korean Journal of Medicine
2012;83(6):823-827
- CountryRepublic of Korea
- Language:English
-
Abstract:
Multiple myeloma is a monoclonal plasma cell proliferation disorder with various symptoms and signs caused by paraproteinemias. Among these signs, a bleeding tendency is one of the major fatal causes. However, significant severe bleeding is rare in most cases. In this study, we report a case of multiple myeloma in a patient who had a severe recurrent bleeding tendency due to platelet dysfunction caused by paraproteins. After being treated with therapeutic plasma exchange and chemotherapy, the patient's monoclonal protein level decreased and the bleeding stopped.
