A Case of Dermatomyositis with Focal Segmental Glomerulosclerosis.
- Author:
Sung In YU
1
;
Min Hee KIM
;
Hyojeong CHANG
;
Sang Hyun KIM
;
Won Do PARK
;
Seong Hoon HAN
;
Hyun Jung KIM
Author Information
1. Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. shan@paik.ac.kr
- Publication Type:Case Report
- Keywords:
Dermatomyositis;
Glomerulosclerosis, Focal Segmental
- MeSH:
Biopsy;
Dermatomyositis;
Edema;
Glomerulonephritis;
Glomerulonephritis, Membranous;
Glomerulosclerosis, Focal Segmental;
Humans;
Lower Extremity;
Middle Aged;
Muscle Weakness;
Polymyositis;
Proteinuria
- From:Korean Journal of Medicine
2012;83(6):828-831
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 59-year-old man visited our hospital for facial edema and muscle weakness in both lower extremities. He was diagnosed with dermatomyositis (DM) about 1 year previously, and sudden development of proteinuria was noted. Renal biopsy revealed focal global and segmental glomerulosclerosis with slight mesangial expansion. Glomerulonephritis is rare in DM. According to our review of related literature, membranous nephropathy is the main type of DM, while mesangial proliferative glomerulonephritis is the most common type in polymyositis. The mechanism underlying the association between DM and glomerulonephritis remains to be elucidated. We herein report a case of DM associated with focal segmental glomerulosclerosis, which has not been reported previously.
