Epithelioid Angiomyolipoma of the Kidney: A case report.
- Author:
You Kyung KIM
;
Jong Sil LEE
;
Ky Hyun CHUNG
;
Sun Hoo PARK
;
Gyung Hyuck KO
- Publication Type:Case Report
- Keywords:
Epithelioid angiomyolipoma;
Kidney
- MeSH:
Actins;
Adipose Tissue;
Aged;
Angiomyolipoma*;
Blood Vessels;
Cytoplasm;
Desmin;
Eosinophils;
Epithelioid Cells;
Estrogens;
Female;
Giant Cells;
Glycogen;
Hamartoma;
Humans;
Keratins;
Kidney*;
Melanosomes;
Mitochondria;
Mucin-1;
Muscle, Smooth;
Receptors, Progesterone;
Tuberous Sclerosis;
Vimentin
- From:Korean Journal of Pathology
2000;34(11):953-956
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Angiomyolipoma is considered by many authors to be a hamartoma, occurring in a sporadic form or in association with tuberous sclerosis. This lesion consists of thick walled blood vessels, smooth muscle, and mature adipose tissue in varying amounts. We have experienced a case of the angiomyolipoma composed of monotypic epithelioid cells. The patient was a 69-year-old female. Clinically, there was no evidence of tuberous sclerosis. Microscopically, the tumor was composed of polygonal cells with abundant eosinophilic granular or clear cytoplasm, pleomorphic nuclei, prominent nucleoli, and multinucleated giant cells. The tumor cells showed positive reaction for HMB45, CD68, smooth muscle actin, and S-100, and negative reaction for epithelial membrane antigen, cytokeratin, vimentin, desmin, CD34, estrogen receptor, and progesterone receptor. Ultrastructual analysis showed the presence of glycogen, mitochondria, and other microorganelles in neoplastic cells. Melanosome or premelanosome was not identified.
