Autoimmune Hemolytic Anemia in Children.
10.3349/ymj.1987.28.4.313
- Author:
Dong Chul PARK
1
;
Chang Hyun YANG
;
Kir Young KIM
Author Information
1. Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Autoimmune hemolytic anemia (AHA);
Evans syndrome;
Guillain-Barre syndrome;
warm antibody;
cold antibody;
Coombs' test
- MeSH:
Adolescent;
Anemia, Hemolytic, Autoimmune/blood;
Anemia, Hemolytic, Autoimmune/diagnosis*;
Anemia, Hemolytic, Autoimmune/therapy;
Child;
Child, Preschool;
Coombs' Test;
Female;
Human;
Infant;
Male;
Retrospective Studies
- From:Yonsei Medical Journal
1987;28(4):313-321
- CountryRepublic of Korea
- Language:English
-
Abstract:
The purpose of this study was to review the clinical hematological, immunological features and treatment responsiveness in children with autoimmune hemolytic anemia (AHA). Eight children with AHA and positive Coombs' test was evaluated. Seven patients presented with acute onset of symptoms and histories of infection. One case was diagnosed as Evans syndrome, one as a chromosomal anomaly, and one case was combined with the Guillain-Barre syndrome. Among 8 the patients, 4 exhibited warm antibodies and the remainder had cold antibodies. The patients were given washed packed red blood cells, prednisolone or immunosuppressive drugs (6-MP or cyclophosphamide). Five patients responded well to transfusion and/or prednisolone, one patient died and one patient showed no response in 5 months of follow up.
