Venous Complications after Pediatric Liver Transplantation.
- Author:
Eun Hee LEE
1
;
Soo Hee CHANG
;
Kyung Mo KIM
;
Kie Young PARK
;
Kyu Bo SUNG
;
Chong Hyun YOON
;
Ki Hun KIM
;
Kwang Min PARK
;
Shin HWANG
;
Chul Soo AHN
;
Young Joo LEE
;
Sung Gyu LEE
Author Information
1. Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. kmkim@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Liver transplantation;
Child;
Portal vein thrombosis;
Hepatic vein stenosis
- MeSH:
Angiography;
Angioplasty;
Ascites;
Cadaver;
Child;
Constriction, Pathologic;
Hemorrhage;
Hepatic Artery;
Hepatic Veins;
Humans;
Incidence;
Liver Transplantation*;
Liver*;
Living Donors;
Mortality;
Portacaval Shunt, Surgical;
Portal Vein;
Reoperation;
Retrospective Studies;
Splenomegaly;
Survival Rate;
Transplants;
Ultrasonography, Doppler;
Venous Thrombosis
- From:The Journal of the Korean Society for Transplantation
2003;17(2):197-202
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We performed this study to assess the incidence of venous complications, including portal vein and hepatic vein stenosis, in both split cadaveric and living donor liver transplants and to assess the diagnostic and therapeutic modalities of these lesions. METHODS: Seventy-six liver transplantations were performed in 75 children with split (5) or living donor (71) graft between December 1994 and March 2002. Patients' data were analyzed retrospectively with special emphasis on venous complications. RESULTS: Venous complications occurred in 14 patients (18.6%) including hepatic vein stenosis in 8, portal vein stenosis in 4, portal vein thrombosis in 1, and combined portal vein thrombosis and hepatic artery stenosis in 1 patient. Venous complications were accompanied by abnormality of liver fuction, ascites, progressed splenomegaly, and gastrointestinal bleeding. To diagnose the venous complications, Doppler ultrasonography was performd at first, and those were confirmed by angiography or CT. Hepatic vein stenosis was managed by percutaneous transhepatic angioplasty (6), angioplasty followed by reposition of graft (1), and supportive care only 1 patient. Portal vein complications were managed by angioplasty (4), angioplasty followed by mesocaval shunt (1), and combined revascularization and angioplasty (1). The overall survival rate was 86% (12 of 14 patients). CONCLUSION: Close surveillance of the complication of vascular anastomoses and multidisciplinary approach to treat of venous complication after pediatric liver transplantation have made it possible to reduce the graft loss and mortality. Aggressive and successful radiologic intervention should be considered to eliminate the need for surgical revision, portacaval shunting or retransplantation.
