Comorbidity of gynecological and non-gynecological diseases with adenomyosis and endometriosis.
10.5468/ogs.2017.60.6.579
- Author:
Eun Ji CHOI
1
;
Seong Beom CHO
;
Sa Ra LEE
;
Young Mi LIM
;
Kyungah JEONG
;
Hye Sung MOON
;
Hyewon CHUNG
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Ewha Womans University, Seoul, Korea. sarahmd@ewha.ac.kr
- Publication Type:Meta-Analysis ; Original Article
- Keywords:
Adenomyosis;
Anemia;
Comorbidity;
Endometriosis;
Hypercholesterolemia
- MeSH:
Adenomyosis*;
Anemia;
Classification;
Comorbidity*;
Endometriosis*;
Female;
Follow-Up Studies;
Humans;
Hypercholesterolemia;
Insurance, Health;
International Classification of Diseases;
Leiomyoma;
Methods;
Prevalence
- From:Obstetrics & Gynecology Science
2017;60(6):579-586
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: Adenomyosis and endometriosis are relatively common gynecological diseases that exhibit many common features. This study identified gynecological and non-gynecological diseases that exhibited comorbidity with adenomyosis and endometriosis in Korean women. METHODS: We used Health Insurance Review and Assessment data from 2009 to 2011 and searched for adenomyosis and endometriosis (coded as N80.1 and D25 in International Classification of Disease, 10th revision [ICD-10], respectively). We selected records from patients who had independent disease occurrences in each year, and comorbidities were estimated using Fisher's exact test. We computed each year's similarities and combined 3 years' results using Fisher's P-value summation method. RESULTS: A total of 61,516 patients' data were collected during the study period. The prevalence of adenomyosis and endometriosis were similar each year: 12.4% and 9.3% in 2009, 12.5% and 9.4% in 2010 and 13.3% and 9.1% in 2011, respectively. Meta-analysis revealed that 31 ICD-10 codes were significantly related with adenomyosis, and 44 ICD-10 codes were related with endometriosis. Gynecological diseases, such as leiomyoma and benign ovarian tumor, were significantly related to adenomyosis and endometriosis. Non-gynecological diseases, such as anemia and hypercholesterolemia, were also related to adenomyosis and endometriosis. CONCLUSION: We must monitor for the presence of gynecological and non-gynecological diseases with co-morbidities during evaluations and follow-up of patients with adenomyosis or endometriosis.
