Ductal Breast Carcinoma Metastatic to the Stomach Resembling Primary Linitis Plastica in a Male Patient.
10.4048/jbc.2016.19.3.324
- Author:
Biagio RICCIUTI
1
;
Giulia Costanza LEONARDI
;
Noemi RAVAIOLI
;
Andrea DE GIGLIO
;
Marta BRAMBILLA
;
Enrico PROSPERI
;
Franca RIBACCHI
;
Marialuisa MEACCI
;
Lucio CRINÒ
;
Daniele MAIETTINI
;
Rita CHIARI
;
Giulio METRO
Author Information
1. Department of Medical Oncology, Santa Maria della Misericordia Hospital, Perugia, Italy. biagio.ricciuti@gmail.com
- Publication Type:Case Report
- Keywords:
Biomarkers;
Breast neoplasms;
Human epidermal growth factor receptor 2;
Linitis plastica;
Neoplasm metastasis
- MeSH:
Antibodies;
Biomarkers;
Breast Neoplasms*;
Breast*;
Cadherins;
Carcinoma, Ductal;
Carcinoma, Lobular;
Carrier Proteins;
Diagnosis, Differential;
Estrogens;
Gastrointestinal Tract;
Humans;
Keratin-20;
Keratin-7;
Linitis Plastica*;
Male*;
Neoplasm Metastasis;
Receptors, Progesterone;
Stomach*
- From:Journal of Breast Cancer
2016;19(3):324-329
- CountryRepublic of Korea
- Language:English
-
Abstract:
Breast cancer metastases to the gastrointestinal tract are very rare occurrences. Among the histological subtypes of breast cancer, invasive lobular carcinomas have a high capacity of metastasis to uncommon sites including the stomach. Conversely, there has not been sufficient evidence supporting the gastric metastasis of invasive ductal carcinoma. Herein, we report a unique case of metastatic ductal breast carcinoma mimicking primary linitis plastica in a male patient, particularly focusing on the clinical and pathological features of presentation. Moreover, we propose a immunohistochemical panel of selected antibodies including those for cytokeratin 20, cytokeratin 7, estrogen receptor, progesterone receptor, E-cadherin, gross cystic disease fluid protein 15, and GATA binding protein 3 for an accurate differential diagnosis.
