A Case of Acute Colchicine-induced Myopathy with Myotonia in Behcet Disease.
- Author:
Se Ho OH
1
;
In Soo JOO
;
Sung Yeol JOO
;
Ewn So LEE
;
Chull SHIM
;
Jang Hee KIM
Author Information
1. Department of Neurology, College of Medicine, Ajou University, 5 San Woncheon-dong, Paldal-gu, Suwon-si, 442-749, Korea. isjoo@madang.ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Colchicine;
Myopathy;
Myotonia
- MeSH:
Adult;
Autoimmune Diseases;
Behcet Syndrome*;
Biopsy;
Colchicine;
Hand Strength;
Humans;
Muscular Diseases*;
Myalgia;
Myotonia*;
Myotonic Disorders;
Relaxation
- From:Journal of the Korean Neurological Association
2003;21(2):220-223
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Colchicine has been used in the treatment of autoimmune diseases such as Behcet disease. Long-term use of colchicine can cause vacuolar myopathy on rare occasions. We report colchicine-induced myopathy with myotonia in Behcet disease. A 34-year-old man with Behcet disease presented progressive proximal weakness, myalgia, and difficulty in relaxation of grip after increasing the dosage of colchicine. Electrophysiological findings showed myotonic myopathy. Muscle biopsy revealed vacuolar myopathy. His symptoms were resolved with the discontinuation of colchicine.
