A Case of Tardive Blepharospasm.
- Author:
Seong Ryong WOO
1
;
Seok Young JEONG
;
Eui Seong LIM
;
Seul Ki JEONG
;
Man Wook SEO
Author Information
1. Department of Neurology, Chonbuk National University Medical School, Jeonju, Korea. smw@chonbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Blepharospasm;
Chlorpromazine;
Atypical antipsychotics
- MeSH:
Adolescent;
Adult;
Blepharospasm*;
Blinking;
Chlorpromazine;
Clozapine;
Dystonic Disorders;
Humans;
Schizophrenia
- From:Journal of the Korean Neurological Association
2005;23(4):565-567
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Blepharospasm is a focal dystonia that consists of repetitive involuntary spasmodic contractions of the orbicularis oculi muscle. A 27-year-old man was admitted with ptosis and involuntary blinking in both eyes. He was diagnosed as having schizophrenia when he was 15 years old and medicated with chlorpromazine for 12 years. After excluding all the possible etiopathological causes of the blepharospam, the offending drug was discontinued and changed to an atypical antipsychotic, clozapine. Clozapine was increased up to 75 mg in the 7th day of admission, and the symptoms were slowly ameliorated.
