Three Cases of Porokeratosis of Mibelli Treated with 5% Imiquimod Cream.
- Author:
Je Ho YEON
1
;
Hyun Sun PARK
;
Kwang Hyun CHO
Author Information
1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea. khcho@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Imiquimod;
Porokeratosis of Mibelli
- MeSH:
Acitretin;
Cryosurgery;
Etretinate;
Fluorouracil;
Humans;
Lasers, Gas;
Porokeratosis*
- From:Korean Journal of Dermatology
2007;45(9):942-946
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Porokeratosis is a disorder of epidermal keratinization that is histologically characterized by the presence of cornoid lamella. Many treatment modalities have been used, such as, surgical excision, cryosurgery, CO2 laser, oral etretinate, topical 5-fluorouracil and keratolytics. However, universal treatment guidelines have never been established. We tried 5% imiquimod cream on three patients who have porokeratosis of Mibelli which are intractable to other previous treatment modalities. Two of them showed a marked and moderate improvement, respectively. But the third patient exhibited only slight response. Herein we report our treatment experience and review the related literature.
