Diffuse Leiomyomatosis of the Uterus: A Brief Case Report.
- Author:
Su Jin KIM
1
;
Mee Sook ROH
Author Information
1. Department of Pathology, Dong-A University College of Medicine, Busan, Korea. msroh@netian.com
- Publication Type:Case Report
- Keywords:
Leiomyomatosis;
Leiomyoma;
Ki-67;
Sex steroid receptor;
Uterus
- MeSH:
Adult;
Animals;
Estrogens;
Female;
Follow-Up Studies;
Humans;
Hysterectomy;
Leiomyoma;
Leiomyomatosis*;
Mice;
Muscle, Smooth;
Myocytes, Smooth Muscle;
Myometrium;
Receptors, Progesterone;
Recurrence;
Uterus*
- From:Korean Journal of Pathology
2005;39(1):63-65
- CountryRepublic of Korea
- Language:English
-
Abstract:
Diffuse leiomyomatosis of the uterus is a rare condition that is distinguished from the uterine leiomyoma due to the diffuse involvement of the myometrium by numerous, ill-defined, smooth muscle nodules. We present here a case of diffuse uterine leiomyomatosis in a 34-year-old woman. The hysterectomy revealed a symmetrically enlarged uterus containing numerous, small, ill-defined leiomyomatous nodules. Microscopically, the nodules were composed of compact fascicles and interweaving bundles of uniform benign smooth muscle cells. On the immunohistochemical staining, the progesterone receptor level was higher in the leiomyomatosis than in the adjacent normal myometrial tissue, but the estrogen receptor level and Ki-67 labeling index were equal in both areas. At the twelve months follow-up, this patient has been doing very well with no evidence of pelvic or intraabdominal recurrence of disease.
