Acquired hemophilia successfully treated with oral immunosuppressive therapy.
- Author:
Je Jung LEE
1
;
Ik Joo CHUNG
;
Moo Rim PARK
;
Duc Hwan YANG
;
Sang Hee CHO
;
Dong Wook RYANG
;
Hyeoung Joon KIM
Author Information
1. Department of Internal Medicine, Chonnam National University Medical School, Kwangju, Korea.
- Publication Type:Case Report
- Keywords:
Acquired hemophilia;
Factor VIII inhibitor;
Immunosuppressive therapy
- MeSH:
Administration, Oral;
Adult;
Case Report;
Cyclophosphamide/therapeutic use+ACo-;
Female;
Hemophilia A/drug therapy+ACo-;
Human;
Immunosuppressive Agents/therapeutic use+ACo-;
Prednisone/therapeutic use+ACo-
- From:The Korean Journal of Internal Medicine
2000;15(2):135-137
- CountryRepublic of Korea
- Language:English
-
Abstract:
Acquired hemophilia is a rare disorder associated with serious bleeding in nonhemophilic patients. We had a 40-year-old woman who was diagnosed as acquired hemophilia with a factor VIII inhibitor level of 27.5 BU/mL. She was presented with gross hematuria and severe right shoulder pain, and was successfully treated with daily oral cyclophosphamide and prednisone for 2 weeks. After the remission, the doses of prednisone and cyclophosphamide were slowly decreased and she remained in complete remission without further bleeding episodes.