Double Primary Gastrointestinal Stromal Tumor Associated with Upper Gastrointestinal Bleeding.
- Author:
Myung Im KIM
1
;
Young Woon CHANG
;
Seok Ho DONG
;
Kyoung Bun PARK
;
Dong Kuen LEE
;
Kyeong Jin KIM
;
Hyo Jong KIM
;
Byung Ho KIM
;
Joung Il LEE
;
Rin CHANG
Author Information
1. Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Gastrointestinal stromal tumor (GIST);
Melena
- MeSH:
Abdomen;
Aged, 80 and over;
Anemia;
Duodenum;
Endoscopy, Digestive System;
Gastrointestinal Stromal Tumors*;
Hemorrhage*;
Humans;
Intestine, Small;
Leiomyoma;
Male;
Melena;
Neurilemmoma;
Stomach
- From:Korean Journal of Gastrointestinal Endoscopy
2000;21(1):554-558
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The terms "gastrointestinal stromal tumor" (GIST) have been applied to mesenchymal tumos that represent neither typical leiomyoma nor schwannoma. The majority of GISTs are Located in the stomach and small intestine, and only 4% of GISTs are found in duodenum. The most important characteristic is their indolent, slow-growing nature, rendering the most common definitions of malignancy invalid and inapplicable. Clinical and pathological criteria to differentiate benign from malignant GISTs are not well established. Tumor size and mitoic activity are commonly considered as important features, allowing for the prediction of biological behaviour and outcome. The case of a 87-year-old male patient who was presented with melena and acute anemia is herein reported. Esophagogastroduodenoscopy and computed tomography of the abdomen revealed two submucosal tumors in the stomach and duodenum. Histological and immunohistochemical studies on the surgical resection specimen revealed a gastrointestinal stromal tumor of an uncommiteed type, with no evidence of increased mitotic activity. The patient was treated with local excision of the tumors and is now in a favorable state.
