Fluid complementation by isotonic saline and hypoisotonic saline (half concentration saline) solutions for treatment of hyperosmalar coma due to diabetes
- Author:
Nguyen Dat Anh
- Publication Type:Journal Article
- Keywords:
coma
- MeSH:
Coma;
therapeutics
- From:Journal of Vietnamese Medicine
2002;269(2):1-10
- CountryViet Nam
- Language:Vietnamese
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Abstract:
Study on 22 nonketonic hyperosmolar coma patients (13 males and 9 females) at the B¹ch Mai hospital during the period from 6/98 to 5/99. Patients were followed a volume replacement protocol using a normal saline during 3 first hours and a half - strength saline solution after that until the plasma osmolatty restores a preset value ((320 mOsmol/kg). Results shown that 17 patients (77%) were treated successfully and discharged. 5 deaths (23%) were seen in study: 1 patient died within the first 12 hours, when he had been presenting an uncontrolled hyperosmolar condition; 4 others died from different causes (such as septic shock, cerebral infarction...). Conclusion: fluid challenge with normal saline and half - strength saline solutions in our study shown a high efficiency in management of nonketotic hyperosmolar coma of NIDDM and did not evoke any serious complications
