Comparison of Thiopental Sodium and Ketamine Induction on Emergence Agitation after Desflurane Anesthesia in Children undergoing a Tonsillectomy.
10.4097/kjae.2007.53.3.356
- Author:
Han Seok KIM
1
;
Soo Kyung LEE
;
Hyo Seok KANG
;
Young Mi KIM
;
Hyun CHOI
;
Hyun Soo MOON
Author Information
1. Department of Anesthesiology and Pain Medicine, College of Medicine, Hallym University, Anyang, Korea. agnetask@yahoo.co.kr
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
desflurane;
emergence agitation;
ketamine;
thiopental
- MeSH:
Adenoidectomy;
Anesthesia*;
Child*;
Dihydroergotamine*;
Humans;
Incidence;
Ketamine*;
Thiopental*;
Tonsillectomy*
- From:Korean Journal of Anesthesiology
2007;53(3):356-360
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUNDs: It is widely known that desflurane provides fast emergence but with a high incidence of emergence agitation. This study was designed to investigate the emergence agitation resulting from thiopental or ketamine induction with desflurane anesthesia for pediatric patients. METHODS: Forty patients, aged 3-8 years, scheduled for a tonsillectomy or a tonsillectomy and adenoidectomy were randomly allocated into two groups. Anesthesia was induced using 5 mg/kg thiopental sodium (Group T patients) or 2 mg/kg ketamine (Group K patients), and was maintained using O2-N2O-desflurane. The recovery time and incidence of emergence agitation were assessed. RESULTS: The incidence of emergence agitation was less in patients in the ketamine induction group. There were no differences in the recovery time and reported side effects. CONCLUSIONS: We conclude that ketamine induction provides less emergence agitation when compared to thiopental induction for desflurane anesthesia for a pediatric tonsillectomy or a tonsillectomy and adenoidectomy without delayed recovery.
