Practice patterns in the management of threatened preterm labor in Korea: A multicenter retrospective study.
10.5468/ogs.2015.58.3.203
- Author:
Han Sung HWANG
1
;
Sung Hun NA
;
Sung Eun HUR
;
Soon Ae LEE
;
Kyung A LEE
;
Geum Joon CHO
;
Kwan Young OH
;
Chan Hee JIN
;
Seung Mi LEE
;
Jae Eun SHIN
;
Kyo Hoon PARK
;
Ji Young LIM
;
Suk Joo CHOI
;
Joon Ho LEE
;
Sae Kyung CHOI
;
Jae Yoon SHIM
;
Yun Sung JO
;
Gyu Yeon CHOI
;
Young Han KIM
;
Ki Cheol KIL
;
Jong Woon KIM
;
Dong Wook KWAK
;
Yun Dan KANG
;
Young Ju KIM
Author Information
1. Department of Obstetrics and Gynecology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
- Publication Type:Multicenter Study ; Original Article
- Keywords:
Clinical practical pattern;
Pregnancy outcome;
Premature birth;
Threatened preterm labor
- MeSH:
Adrenal Cortex Hormones;
Anti-Bacterial Agents;
Back Pain;
Betamethasone;
Calcium Channel Blockers;
Dexamethasone;
Diagnosis;
Female;
Humans;
Korea;
Magnesium Sulfate;
Muscle Cramp;
Obstetric Labor, Premature*;
Physician's Practice Patterns;
Pregnancy;
Pregnancy Outcome;
Pregnant Women;
Premature Birth;
Retrospective Studies*;
Tocolysis;
Tocolytic Agents;
Uterine Contraction;
Vaginal Discharge
- From:Obstetrics & Gynecology Science
2015;58(3):203-209
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: This study aimed to examine clinical practice patterns in the management of pregnant women admitted with threatened preterm labor (TPL) in Korea. METHODS: Data from women admitted with a diagnosis of TPL were collected from 22 hospitals. TPL was defined as regular uterine contractions with or without other symptoms such as pelvic pressure, backache, increased vaginal discharge, menstrual-like cramps, bleeding/show and cervical changes. Data on general patient information, clinical characteristics at admission, use of tocolytics, antibiotics, and corticosteroids, and pregnancy outcomes were collected using an online data collections system. RESULTS: A total of 947 women with TPL were enrolled. First-line tocolysis was administered to 822 (86.8%) patients. As a first-line tocolysis, beta-agonists were used most frequently (510/822, 62.0%), followed by magnesium sulfate (183/822, 22.3%), calcium channel blockers (91/822, 11.1%), and atosiban (38/822, 4.6%). Of the 822 women with first-line tocolysis, second-line tocolysis were required in 364 (44.3%). Of 364 with second-line, 199 had third-line tocolysis (37.4%). Antibiotics were administered to 29.9% of patients (284/947) with single (215, 22.7%), dual (26, 2.7%), and triple combinations (43, 4.5%). Corticosteroids were administered to 420 (44.4%) patients. Betamethasone was administered to 298 patients (71.0%), and dexamethasone was administered to 122 patients (29.0%). CONCLUSION: Practice patterns in the management of TPL in Korea were quite various. It is needed to develop standardized practice guidelines for TPL management.
